Advertisement
Research Article| Volume 117, ISSUE 3, P272-275, March 1995

Download started.

Ok

Surgery for adult polycystic liver disease

      This paper is only available as a PDF. To read, Please Download here.
      Background. Occasionally patients with adult polycystic liver disease (APLD) have symptoms. For these patients surgery may represent a valuable therapeutic option to relieve symptoms.
      Methods. From September 1977 to August 1993 at our institution, 10 women with APLD were examined and surgically treated. They underwent a partial hepatic resection together with cyst fenestration. The surgical outcome and long-term follow-up were retrospectively analyzed.
      Results. Postoperative morbidity consisted of one case of pneumonia, and one case of acute pancreatitis with deep vein leg thrombosis. One patient died after acute Budd-Chiari syndrome developed as a result of liver collapse after fenestration of a posterior cyst. In the long term six of nine patients were symptom free. Late surgical complications included acute cholecystitis (one patient), small bowel obstruction (one), and incisional hernia (two).
      Conclusions. A combined surgical approach of hepatic resection and cyst fenestration has proved feasible for patients with highly symptomatic APLD. Extensive fenestration of posterior cysts should be avoided; transverse hepatic resection (frontal hepatectomy) up to the costal margin is proposed. This therapy provides good results at long-term follow-up.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • JN Vauthey
        • Maddern GJ
        • Blumgart LH
        Adult polycystic disease of the liver.
        Br J Surg. 1991; 78: 524-527
        • Armitage NC
        • Blumgart LH
        Partial resection and fenestration in the treatment of polycystic liver disease.
        Br J Surg. 1984; 71: 242-244
        • Iwatsuki S
        • Starzl TE
        Personal experience with 411 hepatic resections.
        Ann Surg. 1988; 208: 421-434
        • Newman KD
        • Torres VE
        • Rakela J
        • Nagorney DM
        Treatment of highly symptomatic polycystic liver disease.
        Ann Surg. 1990; 212: 30-37
        • Sanchez H
        • Gagner M
        • Rossi RL
        • et al.
        Surgical management of nonparasitic cystic liver disease.
        Am J Surg. 1991; 161: 113-119
        • Vauthey JN
        • Maddern GJ
        • Kolbinger P
        • Baer HU
        • Blumgart LH
        Clinical experience with adult polycystic liver disease.
        Br J Surg. 1992; 79: 562-565
        • Henne-Bruns D
        • Klomp HJ
        • Kremer B
        Non-parasitic liver cysts and polycystic liver disease results of surgical treatment.
        Hepatogastroenterology. 1993; 40: 1-5
        • Martinod E
        • Zoghby J
        • Vons C
        • Chauveau D
        • Grunfeld JP
        • Franco D
        Résection hépatique pour polykystose hépato-rénale.
        Ann Chir. 1993; 47 ([Abstract]): 1058
        • Trinkl W
        • Sassaris M
        • Hunter FM
        Nonsurgical treatment for symptomatic nonparasitic liver cyst.
        Am J Gastroenterol. 1985; 80: 907-911
        • Kairoluoma MI
        • Leinonen A
        • Stahlberg M
        • Paivansalo M
        • Kiviniemi H
        • Siniluoto T
        Percutaneous aspiration and alcohol sclerotherapy for symptomatic hepatic cysts.
        Ann Surg. 1989; 210: 208-215
        • Lin TY
        • Chen CC
        • Wang SM
        Treatment of non-parasitic cystic disease of the liver: a new approach to therapy with polycystic liver.
        Ann Surg. 1968; 168: 921-927
        • Bismuth H
        Surgical anatomy and anatomical surgery of the liver.
        World J Surg. 1982; 6: 3-9
        • Karhunen PJ
        Adult polycystic liver disease and biliary microhamartomas (Von Meyenburg's complexes).
        Acta Pathol Microbiol Immunol Scand. 1986; 94: 397-400
        • Kwok MK
        • Lewin KJ
        Massive hepatomegaly in adult polycystic liver disease.
        Am J Surg Pathol. 1988; 12: 321-324
        • Milutinovic J
        • Fialkow PI
        • Rudd TG
        • Agodoa LY
        • Philips LA
        • Bryant JI
        Liver cysts in patients with autosomal dominant polycystic kidney disease.
        Am J Med. 1980; 68: 741-744
        • Thomsen HS
        • Thaysen JH
        Frequency of hepatic cysts in adult polycystic kidney disease.
        Acta Med Scand. 1988; 224: 381-384
        • Grunfeld JP
        • Albouzen G
        • Jungers P
        • et al.
        Liver changes and complications in adult polycystic kidney disease.
        Adv Nephrol. 1985; 14: 1-20
        • Peltokallio V
        Non-parasitic cyst of the liver: a clinical study of 117 cases.
        Ann Chir Gynecol. 1970; 59: 1-63
        • Ratcliffe PJ
        • Reeders S
        • Theaker JM
        Bleeding oesophageal varices and hepatic dysfunction in adult polycystic liver disease.
        Br Med J. 1984; 288: 1330-1331
        • Wittig JH
        • Burns R
        • Lonmire WP
        Jaundice associated with polycystic liver disease.
        Am J Surg. 1978; 138: 383-386
        • Iglesias CG
        • Torres VE
        • Offord KP
        • Holley KE
        • Beard CM
        • Kurland LT
        Epidemiology of adult polycystic kidney disease: Olmsted County, Minnesota—1935–1980.
        Am J Kidney Dis. 1983; 2: 630-639
        • Saini S
        • Mueller PR
        • Ferruci JT
        • Simeone JF
        • Wittenberg J
        • Butch RJ
        Percutaneous aspiration of hepatic cysts does not provide definitive therapy.
        AJR. 1983; 141: 559-560
        • Van Erpecum KD
        • Janssen AR
        • Terpstra JL
        • Tham RTO
        Highly symptomatic adult polycystic disease of the liver.
        J Hepatol. 1987; 5: 109-117
        • Morino M
        • De Giuli M
        • Festa V
        • Garrone C
        Laparoscopic managment of symptomatic non parasitic cysts of the liver: indications and results.
        Ann Surg. 1994; 219: 157-164
        • Everson GT
        • Scherzinger A
        • Berger-Leff N
        • et al.
        Polycystic liver disease: quantitation of parenchymal and cysts volumes from computed tomography images and clinical correlates of hepatic cysts.
        Hepatology. 1988; 8: 1627-1634
        • Ambrosetti P
        • Widmann JJ
        • Robert J
        • Rohner A
        Syndrome aigu de Budd-Chiari après traitement chirurgical d'une polykystose hépatique.
        Gastroenterol Clin Biol. 1992; 16: 894-896
        • Pitre J
        • Panis Y
        • Belghiti J
        Left hepatic vein kinking after right hepatectomy: a rare cause of acute Budd-Chiari syndrome.
        Br J Surg. 1992; 79: 798-799
        • Madariaga JR
        • Iwatsuki S
        • Starzl TE
        • Todo S
        • Selby R
        • Zetti G
        Hepatic resection for cystic lesions of the liver.
        Ann Surg. 1993; 218: 610-614
        • Starzl TE
        • Reyes J
        • Tsakis A
        • Mieles L
        • Todo S
        Liver transplantation for polycystic liver disease.
        Arch Surg. 1990; 125: 575-577