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Letter to the Editor| Volume 142, ISSUE 3, P426-427, September 2007

Analysis of efficacy and safety of drotrecogin alfa (activated) in surgical patients, using an international integrated database

      We appreciate the interest de Pont et al have shown in our recent article.
      • Payen D.
      • Sablotzki A.
      • Barie P.S.
      • Ramsay G.
      • Lowry S.
      • Williams M.
      • et al.
      International integrated database for the evaluation of severe sepsis and drotrecogin alfa (activated) therapy: analysis of efficacy and safety data in a large surgical cohort.
      They have raised statistical questions relating to presentation of the data that we would like to address and clarify.
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      Reference

        • Payen D.
        • Sablotzki A.
        • Barie P.S.
        • Ramsay G.
        • Lowry S.
        • Williams M.
        • et al.
        International integrated database for the evaluation of severe sepsis and drotrecogin alfa (activated) therapy: analysis of efficacy and safety data in a large surgical cohort.
        Surgery. 2006; 140: 726-739