Background
Major bile duct injuries remain a potentially devastating complication after laparoscopic
cholecystectomy. A retrospective review was conducted of patients who underwent a
biliary-enteric reconstruction of a biliary injury to assess their long-term outcome.
Methods
Retrospective review of bile duct injury database from January 1990 to December 2005.
Results
A total of 144 patients were treated for bile duct injury, and 84 (58%) required a
biliary-enteric reconstruction. Stratification by Bismuth-Strasberg injury level revealed
E1 or E2 in 23, E3 in 33, E4 in 17, E5 in 1, and B+C in 10. Forty-four (52%) were
operated within 7 days of laparoscopic cholecystectomy, the remainder operated at
a median of 79 days after referral. Early or late mortality occurred in 3 (4%). At
a mean follow-up of 67 months, 9 patients (11%) developed a biliary stricture presented
at a median of 13 months after bile duct repair. Level of injury was very important
in predicting a postoperative biliary stricture: E4 (35%) versus E3 (9%; P = .023), and E4 versus E1, E2 B+C (0%; P = .001). More strictures occurred in patients operated within 7 days of laparoscopic
cholecystectomy (19%) versus delayed repair (8%; P = .053). Overall, 90% of patients are alive and nonstented; 5 patients have chronic
liver disease (1 on the waiting list for liver transplant). Nonbiliary complications
occurred in 15 patients; the total morbidity was 40%.
Conclusions
Bile duct injuries that require a biliary-enteric repair are commonly associated with
long-term complications. Level of injury and likely timing of repair predict risk
of postoperative stricture.
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Article info
Publication history
Accepted:
July 21,
2007
Identification
Copyright
© 2007 Mosby, Inc. Published by Elsevier Inc. All rights reserved.
