Advertisement
Central Surgical Association| Volume 142, ISSUE 4, P588-593.e3, October 2007

Duodenum-preserving head resection for chronic pancreatitis: an institutional experience and national survey of usage

      Background

      Duodenum-preserving pancreatic head resections (DPPHRs) have been shown in European randomized clinical trials to be superior to pancreaticoduodenectomy for chronic pancreatitis, but DPPHR procedures have been slow to be adopted in the United States.

      Methods

      To assess national attitudes of surgeons toward DPPHR, a web-based survey was administered to the U.S. members of the Pancreas Club, which is a national organization of pancreatic surgeons. We also performed a retrospective review of 21 DPPHRs, performed by the senior author, for chronic pancreatitis between January 2000 and March 2005.

      Results

      The web-based national survey was completed by 64 of 118 members of the Pancreas Club (54.24%). Of the 59 surgeons who perform operations for chronic pancreatitis, 34 had performed a DPPHR at least once. Only 23 U.S. surgeons continue to perform these procedures. Most surgeons who are not performing DPPHRs responded that, despite the published literature, existing procedures such as the Whipple and Puestow were better procedures. In our clinical series, 12 men and 9 women with a mean age of 48.2 ± 9.6 years underwent DPPHR. The median length of stay was 9 days with 6 patients (28%) who had complications in the postoperative period. Ten of 20 potentially evaluable patients completed a visual analog pain scale and EORTC C-30 quality-of-life questionnaire. Pancreatic functioning approached the normal range in all domains. As compared with a general population of patients with chronic pancreatitis, significant improvement occurred in pancreatic-related pain and digestive function. Self-reported pain was significantly better after operation than before operation.

      Conclusions

      DPPHR provides excellent functional results with relatively low postoperative morbidity and duration of stay. These procedures are underused in the United States, with very few surgeons who use, teach them, or report their results.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Singh M.
        • Simsek H.
        Ethanol and the pancreas: current status.
        Gastroenterology. 1990; 98: 1051-1062
      1. Copenhagen Pancreatic Study. An interim report from a prospective epidemiological multicenter study. Scand J Gastroenterol 198;16:305-12.

        • Ebbehoj N.
        • Borly L.
        • Madsen P.
        • Svendsen L.B.
        Pancreatic tissue pressure and pain in chronic pancreatitis.
        Pancreas. 1986; 1: 556-558
        • Taylor R.H.
        • Bagley F.H.
        • Braasch J.W.
        • Warren K.W.
        Ductal drainage or resection for chronic pancreatitis.
        Am J Surg. 1981; 141: 28-33
        • Traverso L.W.
        • Kozarek R.A.
        The Whipple procedure for severe complications of chronic pancreatitis.
        Arch Surg. 1993; 128: 1047-1050
        • Frey C.F.
        • Smith G.J.
        Description and rationale of a new operation for chronic pancreatitis.
        Pancreas. 1987; 2: 701-707
        • Beger H.G.
        • Witte C.
        • Krautzberger W.
        • Bittner R.
        [Experiences with duodenum-sparing pancreas head resection in chronic pancreatitis].
        Chirurg. 1980; 51 ([German]): 303-307
        • Izbicki J.R.
        • Bloechle C.
        • Broering D.C.
        • Knoefel W.T.
        • Kuechler T.
        • Broelsch C.E.
        Extended drainage versus resection in surgery for chronic pancreatitis: a prospective randomized trial comparing the longitudinal pancreaticojejunostomy combined with local pancreatic head excision with the pylorus-preserving pancreatoduodenectomy.
        Ann Surg. 1998; 228: 771-779
        • Buchler M.W.
        • Friess H.
        • Muller M.W.
        • Wheatley A.M.
        • Beger H.G.
        Randomized trial of duodenum-preserving pancreatic head resection versus pylorus-preserving Whipple in chronic pancreatitis.
        Amer J Surg. 1995; 169: 65-69
        • Muller M.W.
        • Friess H.
        • Beger H.G.
        • Kleeff J.
        • Lauterburg B.
        • Glasbrenner B.
        • et al.
        Gastric emptying following pylorus-preserving Whipple and duodenum-preserving pancreatic head resection in patients with chronic pancreatitis.
        Am J Surg. 1997; 173: 257-263
        • Andersen D.K.
        • Topazian M.D.
        Pancreatic head excavation: a variation on the theme of duodenum-preserving pancreatic head resection.
        Arch Surg. 2004; 139: 375-379
        • Ritchie Jr, W.P.
        • Rhodes R.S.
        • Biester T.W.
        Work loads and practice patterns of general surgeons in the United States, 1995-1997: a report from the American Board of Surgery.
        Ann Surg. 1999; 230: 533-542
        • Aaronson N.K.
        • Ahmedzai S.
        • Bergman B.
        • Bullinger M.
        • Cull A.
        • Duez N.J.
        • et al.
        The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology.
        J Natl Cancer Inst. 1993; 85: 365-376
        • Fitzsimmons D.
        • Kahl S.
        • Butturini G.
        • van Wyk M.
        • Bornman P.
        • Bassi C.
        • et al.
        Symptoms and quality of life in chronic pancreatitis assessed by structured interview and the EORTC QLQ-C30 and QLQ-PAN26.
        Am J Gastroenterol. 2005; 100: 918-926
        • Strate T.
        • Taherpour Z.
        • Bloechle C.
        • Mann O.
        • Bruhn J.P.
        • Schneider C.
        • et al.
        Long-term follow-up of a randomized trial comparing the Beger and Frey procedures for patients suffering from chronic pancreatitis.
        Ann Surg. 2005; 241: 591-598
        • Witzigmann H.
        • Max D.
        • Uhlmann D.
        • Geissler F.
        • Ludwig S.
        • Schwarz R.
        • et al.
        Quality of life in chronic pancreatitis: a prospective trial comparing classical Whipple procedure and duodenum-preserving pancreatic head resection.
        J Gastrointestinal Surg. 2002; 6: 173-179
        • Hjermstad M.J.
        • Fayers P.M.
        • Bjordal K.
        • Kaasa S.
        Using reference data on quality of life--the importance of adjusting for age and gender, exemplified by the EORTC QLQ-C30 (+3).
        Eur J Cancer. 1998; 34: 1381-1389
        • Kennedy T.
        • Preczewski L.
        • Stocker S.J.
        • Rao S.M.
        • Parsons W.G.
        • Wayne J.D.
        • et al.
        Incidence of benign inflammatory disease in patients undergoing Whipple procedure for clinically suspected carcinoma: a single-institution experience.
        Am J Surg. 2006; 191: 437-441
        • Makowiec F.
        • Riediger H.
        • Hopt U.T.
        • Adam U.
        Randomized controlled trial of pylorus-preserving Whipple versus duodenum-preserving pancreatic head resection in chronic pancreatitis.
        2004 (Presented at the Pancreas Club meeting, New Orleans, LA)

      Linked Article

      • Erratum
        SurgeryVol. 143Issue 2
        • Preview
          As a result of a production error, several articles appearing in the Central Surgical Association (Surgery, 2007; Vol. 142, No. 4:433-644) and American Association of Endocrine Surgeons (Surgery, 2007; Vol. 142, No. 6:785-1030) special focus issues were published without their respective discussions. The articles affected have now been updated online to include the missing discussion material. Surgery apologizes to the authors for this significant oversight.
        • Full-Text
        • PDF