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A 38-year-old woman presented with a 3-week history of a painless lump in her neck. She denied history
of trauma, fever, radiation exposure, or a preceding upper respiratory tract infection.
Her family history was significant in that her mother had benign nodular goiter. The
patient was otherwise in good health. On palpation, the right lobe was enlarged and
firm with minimal tenderness. Thyroid function was within normal limits. Thyroid ultrasound
showed a 1.5 × 1.1-cm hypoechoic mass at the right lobe, with an irregular and poorly
defined border. No cervical lymphadenopathy was detected. Fine-needle aspiration cytology
was insufficient for diagnosis. Based on suspicious ultrasonographic characteristics,
a right lobectomy was performed (Fig 1). Histopathologic examination showed a mixed inflammatory infiltrate with some multinucleate
giant cells (Fig 2). She is euthyroid without recurrence after 2 years of follow-up.
Fig 1Photograph showing the gross appearance of the cut surface of the thyroid tumor. The
yellow-white lesion has an irregular margin.
Fig 2Photomicrograph (hematoxylin-eosin, original magnification × 100) showing chronic
inflammation and prominent fibrosis with some multinucleated giant cells. There is
no caseous necrosis. Residual follicles are present.
