Background
Transplantation of kidneys from deceased donors with terminal acute renal failure
(ARF) is uncommon.
Methods
We reviewed retrospectively our single-center experience with transplantation of ARF
donor kidneys.
Results
From January 2007 through September 2008, we transplanted 25 kidneys from 17 ARF donors;
22 kidneys were from standard criteria donors. Mean donor age was 34 years. Mean admission
and terminal donor serum creatinine values were 1.3 mg/dL and 3.1 mg/dL. All but 2
kidneys were placed on pump preservation; mean cold ischemia time was 27 hours. The
recipient group had a mean age of 49 years and a mean waiting time of 24 months. Patient
and graft survival rates were 100% and 92%, respectively, with a mean follow-up of
12 months. Delayed graft function occurred in 8 patients (32%), mean initial duration
of stay was 6 days, 3 patients (12%) required re-operation, 3 patients (12%) had acute
rejection, and 8 patients (32%) developed infections. Mean 1- and 12-month recipient
serum creatinine and glomerular filtration rate values were 1.9 mg/dl (45 mL/min)
and 1.5 mg/dl (50 mL/min), respectively.
Conclusion
Kidneys from deceased donors with terminal ARF have excellent short-term outcomes
and represent another potential method to safely expand the donor pool.
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Article info
Publication history
Accepted:
June 5,
2009
Identification
Copyright
© 2009 Mosby, Inc. Published by Elsevier Inc. All rights reserved.
