The scientific world has witnessed a 5-fold increase in the number of published genomic studies of humans
in the past 2 decades. Major advances in genetics, most notably, the completion of
the Human Genome Project in 2001
1
,
2
and the International HapMap Project
3
,
4
,
5
in 2003, in conjunction with the rapid advances of genotyping technology, has made
it more feasible and less expensive for scientists to perform large-scale studies
of genetic epidemiologic associations of common as well as rare diseases. The implications
for patient care are not always readily apparent; but there is an underlying expectation
that these types of studies will contribute to the development of individualized medicine,
where genomic information from each individual is used during consultation to help
tailor the treatment plan to that specific individual. More importantly, these studies
may offer insight into the cause of the disease under study and enhance our potential
for risk stratification, which can ultimately help with local resource allocation.To read this article in full you will need to make a payment
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References
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Article info
Publication history
Published online: December 04, 2009
Accepted:
October 5,
2009
Footnotes
Supported by Grant 1 UL1 RR024150 from the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH), and the NIH Roadmap for Medical Research.
Identification
Copyright
© 2010 Mosby, Inc. Published by Elsevier Inc. All rights reserved.
