An abdominal operation combines a somatic abdominal wall wound with a second autonomic wound to the peritoneal cavity and viscera and little attention has been paid the autonomic/peritoneal wound that communicates directly to the brain by the vagus nerve. Moreover, vagal input originating from the peritoneum modulates and regulates postoperative recovery. Consequently, blockade of the afferent neural and inflammatory input from this autonomic/peritoneal wound will reduce postoperative neurohormonal stress and enhance patient recovery from an abdominal operation.
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- Epidural anaesthesia and analgesia: effects on surgical stress responses and implications for postoperative nutrition.Clin Nutr. 2002; 21: 199-206
- Laparoscopic versus open cholecystectomy for patients with symptomatic cholecystolithiasis.Cochrane Database Syst Rev. 2006; (CD006231)
- Functional recovery after open versus laparoscopic colonic resection: a randomized, blinded study.Ann Surg. 2005; 241: 416-423
- Peritoneal damage: the inflammatory response and clinical implications of the neuro-immuno-humoral axis.World J Surg. 2010; 34: 704-720
- Does the vagus nerve mediate the sixth sense?.Trends Neurosci. 2001; 24: 671-673
- Visceral pain.Lancet. 1999; 353: 2145-2148
- Systemic and peritoneal inflammatory response after laparoscopic or conventional colon resection in cancer patients: a prospective, randomized trial.Dis Colon Rectum. 2003; 46: 147-155
- The net immunologic advantage of laparoscopic surgery.Surg Endosc. 2004; 18: 1411-1419
- A comparison of the inflammatory response and the recovery of bowel function between trans- and extraperitoneal approaches of abdominal aortic aneurysmectomy.Int Angiol. 2005; 24: 355-358
- Differential c-fos expression in the nucleus of the solitary tract and spinal cord following noxious gastric distention in the rat.Neuroscience. 1996; 74: 873-884
- Intraperitoneal local anesthetic improves recovery after colectomy: a double blind randomised controlled trial.Aust N Z J Surg. 2010; (80S1:A15)
- Influences of splanchnic nerve blockade on endocrine-metabolic responses to upper abdominal surgery.Br J Surg. 1983; 70: 437-439
- Randomized clinical trial of the effect of glucocorticoids on peritoneal inflammation and postoperative recovery after colectomy.Br J Surg. 2009; 96: 1253-1261
Published online: December 13, 2010
Accepted: October 25, 2010
© 2011 Mosby, Inc. Published by Elsevier Inc. All rights reserved.