Introduction
There is a paucity of data on outcomes for lung transplant (LT) recipients requiring
general surgery procedures. This study examined outcomes after cholecystectomy in
LT recipients using a large database.
Methods
The National Inpatient Sample Database (2005–2010) was queried for all LT patients
requiring laparoscopic cholecystectomy (LC) and open cholecystectomy (OC).
Results
There were a total of 377 cholecystectomies performed in LT patients. The majority
were done for acute cholecystitis (n = 218; 57%) and were done urgently/emergently (n = 258; 68%). There were a total of 304 (81%) laparoscopic cholecystectomies and 73
(19%) OC. There was no difference in age when comparing the laparoscopic and open
groups (53.6 vs 55.5 years; P = .39). In addition, the Charlson Comorbidity Index was similar in the 2 groups (P = .07). Patients undergoing OC were more likely to have perioperative myocardial
infarction, pulmonary embolus, or any complication compared with the laparoscopic
group. Total hospital charges ($59,137.00 vs $106,329.80; P = .03) and median duration of stay (4.0 vs 8.0 days; P = .02) were both greater with open compared with LC.
Conclusion
Cholecystectomy can be performed safely in the LT population with minimal morbidity
and mortality.
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References
- The Registry of the International Society for Heart and Lung Transplantation: 29th adult lung and heart-lung transplant report-2012.J Heart Lung Transplant. 2012; 31: 1073-1086
- Results of single and bilateral lung transplantation in 131 consecutive recipients. Washington University Lung Transplant Group.J Thorac Cardiovasc Surg. 1994; 107: 460-470
- Double-lung transplantation can be safely performed using donors with heavy smoking history.Ann Thorac Surg. 2013; 95: 1912-1918
- Survival after bilateral versus single lung transplantation for patients with chronic obstructive pulmonary disease: a retrospective analysis of registry data.Lancet. 2008; 371: 744-751
- Acute cholecystitis: early versus delayed cholecystectomy, a multicenter randomized trial.Ann Surg. 2013; 258: 385-393
- A current profile and assessment of North American Cholecystectomy: results from the American College of Surgeons National Surgical Quality Improvement Program.J Am Coll Surg. 2010; 211: 176-186
- Effects of immunosuppressive therapy on wound healing.Int Wound J. 2013; 10: 98-104
- Overview of the National (Nationwide) Inpatient Sample (NIS). Healthcare Cost and Utilization Project (HCUP).Agency for Healthcare Research and Quality, Rockville, MD2014
- Outcomes of cholecystectomy in US heart transplant recipients.Ann Surg. 2013; 258: 312-317
- Examining ABO compatible donors in double lung transplants during the era of lung allocation score.Ann Thorac Surg. 2014; 98: 1167-1174
- Single-lung transplantation with ABO-compatible donors results in excellent outcomes.J Heart Lung Transplant. 2014; 33: 822-828
- Single-lung transplantation can be performed with acceptable outcomes using selected donors with heavy smoking history.J Heart Lung Transplant. 2013; 32: 1005-1012
- The Copenhagen National Lung Transplant Group: survival after single lung, double lung, and heart-lung transplantation.J Heart Lung Transplant. 2005; 24: 1834-1843
- Risk factors for early primary graft dysfunction after lung transplantation: a registry study.Clin Transplant. 2009; 23: 819-830
- Complications of laparoscopic cholecystectomy: a national survey of 4,292 hospitals and an analysis of 77,604 cases.Am J Surg. 1993; 165: 9-14
- Gastrointestinal Complications after Lung Transplantation.Korean J Thorac Cardiovasc Surg. 2010; 43: 280-284
- Abdominal surgery after lung transplantation.Am Surg. 2010; 76: 1130-1134
- Intraabdominal complications after lung transplantation.J Am Coll Surg. 2006; 203: 653-660
- Gastrointestinal complications after lung transplantation.J Heart Lung Transplant. 2009; 28: 475-479
- Management of biliary tract disease in heart and lung transplant patients.Surgery. 2000; 128: 641-649
- Time to lung transplantation: lung allocation score and other factors.J Pulmonar Respirat Med. 2012; 2: e110
- Lung Allocation Score for lung transplantation: impact on disease severity and survival.Chest. 2007; 132: 1954-1961
- Fundoplication after lung transplantation prevents the allograft dysfunction associated with reflux.Ann Thorac Surg. 2011; 92: 462-468
- Randomised trial of laparoscopic versus open cholecystectomy for acute and gangrenous cholecystitis.Lancet. 1998; 351: 321-325
- Gastrointestinal complications in lung transplant survivors that require surgical intervention.Br J Surg. 2001; 88: 433-438
Article info
Publication history
Published online: May 18, 2015
Accepted:
February 28,
2015
Footnotes
The authors have no disclosures to report.
Identification
Copyright
© 2015 Elsevier Inc. Published by Elsevier Inc. All rights reserved.