Advertisement
Trauma/Critical Care| Volume 158, ISSUE 2, P379-385, August 2015

Rate of lower-extremity ultrasonography in trauma patients is associated with rate of deep venous thrombosis but not pulmonary embolism

      Background

      Disparate lower-extremity ultrasonography (LUS) screening practices among trauma institutions reflecta lack of consensus regarding screening indications and whether screening improves outcomes. We hypothesized that LUS screening for deep-vein thrombosis (DVT) is not associated with a reduced incidence of pulmonary embolism (PE).

      Methods

      The 2012 ACS National Trauma Data Bank Research Data Set was queried to identify 442,108 patients treated at institutions reporting at least one LUS and at least one DVT. Institutions performing LUS on more than 2% of admitted patients were designated high-screening facilities and remaining institutions were designated low-screening facilities. Patient characteristics and risk factors were used to develop a logistic regression model to assess the independent associations between LUS and DVT and between LUS and PE.

      Results

      Overall, DVT and PE were reported in 0.94% and 0.37% of the study population, respectively. DVT and PE were reported more commonly in designated high-screening than low-screening facilities (DVT: 1.12% vs 0.72%, P < .0001; PE: 0.40% vs 0.33%, P = .0004). Multivariable logistic regression demonstrated that LUS was associated independently with DVT (odds ratio 1.43, confidence interval 1.34–1.53) but not PE (odds ratio 1.01, confidence interval 0.92–1.12) (c-statistic 0.86 and 0.85, respectively). Sensitivity analyses performed at various rates for designating HS facilities did not alter the significance of these relationships.

      Conclusion

      LUS in trauma patients is not associated with a change in the incidence of PE. Aggressive LUS DVT screening protocols appear to detect many clinically insignificant DVTs for which subsequent therapeutic intervention may be unnecessary, and the use of these protocols should be questioned.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Geerts W.H.
        • Bergqvist D.
        • Pineo G.F.
        • Heit J.A.
        • Samama C.M.
        • Lassen M.R.
        • et al.
        Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th edition).
        Chest. 2008; 133: 381S-453S
        • Haut E.R.
        • Schneider E.B.
        • Patel A.
        • Streiff M.B.
        • Haider A.H.
        • Stevens K.A.
        • et al.
        Duplex ultrasound screening for deep vein thrombosis in asymptomatic trauma patients: a survey of individual trauma surgeon opinions and current trauma center practices.
        J Trauma. 2011; 70 (discussion 33–34): 27-33
        • Rogers F.B.
        • Cipolle M.D.
        • Velmahos G.
        • Rozycki G.
        • Luchette F.A.
        Practice management guidelines for the prevention of venous thromboembolism in trauma patients: the EAST practice management guidelines work group.
        J Trauma. 2002; 53: 142-164
      1. National Trauma Data Bank User Manual. 2013. Avaiable from: https://www.facs.org/qualityprograms/trauma/ntdb/datasets. Accessed August 20, 2014.

        • Haut E.R.
        • Chang D.C.
        • Pierce C.A.
        • Colantuoni E.
        • Efron D.T.
        • Haider A.H.
        • et al.
        Predictors of posttraumatic deep vein thrombosis (DVT): hospital practice versus patient factors-an analysis of the National Trauma Data Bank (NTDB).
        J Trauma. 2009; 66 (discussion 999–1001): 994-999
        • Knudson M.M.
        • Ikossi D.G.
        • Khaw L.
        • Morabito D.
        • Speetzen L.S.
        Thromboembolism after trauma.
        Ann Surg. 2004; 240: 490-498
        • Shackford S.R.
        • Cook A.
        • Rogers F.B.
        • Littenberg B.
        • Osler T.
        The increasing use of vena cava filters in adult trauma victims: data from the American College of Surgeons National Trauma Data Bank.
        J Trauma. 2007; 63: 764-769
        • Pierce C.A.
        • Chang D.C.
        • Pierce C.A.
        • Colantuoni E.
        • Efron D.T.
        • Haider A.H.
        • et al.
        Surveillance bias and deep vein thrombosis in the national trauma data bank: the more we look, the more we find.
        J Trauma. 2008; 64 (discussion 936–937): 932-936
        • Burns G.
        • Cohn S.
        Prospective ultrasound evaluation of venous thrombosis in high-risk trauma patients.
        J Trauma. 1993; 35 (Available from:) (Accessed August 22, 2014)
        • Napolitano L.M.
        • Garlapati V.S.
        • Heard S.O.
        • Silva W.E.
        • Cutler B.S.
        • O'Neill A.M.
        • et al.
        Asymptomatic deep venous thrombosis in the trauma patient: is an aggressive screening protocol justified?.
        J Trauma. 1995; 39 (discussion 657–659): 651-657
        • Meythaler J.M.
        • DeVivo M.J.
        • Hayne J.B.
        Cost-effectiveness of routine screening for proximal deep venous thrombosis in acquired brain injury patients admitted to rehabilitation.
        Arch Phys Med Rehabil. 1996; 77: 1-5
        • Brasel K.J.
        • Borgstrom D.C.
        • Weigelt J.A.
        Cost-effective prevention of pulmonary embolus in high-risk trauma patients.
        J Trauma. 1997; 42 (discussion 460–462): 456-460
        • Piotrowski J.J.
        • Alexander J.J.
        • Brandt C.P.
        • McHenry C.R.
        • Yuhas J.P.
        • Jacobs D.
        Is deep vein thrombosis surveillance warranted in high-risk trauma patients?.
        Am J Surg. 1996; 172: 210-213
        • Cipolle M.D.
        • Wojcik R.
        • Seislove E.
        • Wasser T.E.
        • Pasquale M.D.
        The role of surveillance duplex scanning in preventing venous thromboembolism in trauma patients.
        J Trauma. 2002; 52: 453-462
        • Meyer C.S.
        • Blebea J.
        • Davis K.
        • Fowl R.J.
        • Kempczinski R.F.
        Surveillance venous scans for deep venous thrombosis in multiple trauma patients.
        Ann Vasc Surg. 1995; 9: 109-114
        • Spain D.A.
        • Richardson J.D.
        • Polk H.C.
        • Bergamini T.M.
        • Wilson M.A.
        • Miller F.B.
        Venous thromboembolism in the high-risk trauma patient: do risks justify aggressive screening and prophylaxis?.
        J Trauma. 1997; 42 (discussion 467–469): 463-467
        • Satiani B.
        • Falcone R.
        • Shook L.
        • Price J.
        Screening for major deep vein thrombosis in seriously injured patients: a prospective study.
        Ann Vasc Surg. 1997; 11: 626-629
        • Teixeira P.G.
        • Inaba K.
        • Dubose J.
        • Melo N.
        • Bass M.
        • Belzberg H.
        • et al.
        Measurable outcomes of quality improvement using a daily quality rounds checklist: two-year prospective analysis of sustainability in a surgical intensive care unit.
        J Trauma Acute Care Surg. 2013; 75: 717-721
        • Haut E.R.
        • Lau B.D.
        • Kraenzlin F.S.
        • Hobson D.B.
        • Kraus P.S.
        • Carolan H.T.
        • et al.
        Improved prophylaxis and decreased rates of preventable harm with the use of a mandatory computerized clinical decision support tool for prophylaxis for venous thromboembolism in trauma.
        Arch Surg. 2012; 147: 901-907
        • Haut E.R.
        • Garcia L.J.
        • Shihab H.M.
        • Brotman D.J.
        • Stevens K.A.
        • Sharma R.
        • et al.
        The effectiveness of prophylactic inferior vena cava filters in trauma patients: a systematic review and meta-analysis.
        JAMA Surg. 2014; 149: 194-202