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Endocrine| Volume 165, ISSUE 3, P608-616, March 2019

Comparison of short-term oncologic outcome of robotic thyroid surgery using dynamic risk stratification: A propensity score–matched comparison study

Published:September 13, 2018DOI:https://doi.org/10.1016/j.surg.2018.07.038

      Background

      The long-term oncologic outcome of robotic surgery for thyroid cancer is not well established. The aim of this study was to predict the long-term oncologic outcome of robotic surgery by using dynamic risk stratification in classic papillary thyroid carcinoma.

      Methods

      A total of 444 propensity score–matched pairs of patients with papillary thyroid carcinoma treated with robotic surgery and conventional open surgery were classified into 4 response-to-therapy categories. The results were compared between the robotic surgery and open surgery groups.

      Results

      The median follow-up duration was 60 months. After propensity score matching, the robotic surgery group showed less extensive thyroid surgery and lymph node dissection and a higher proportion of patients who underwent radioactive iodine remnant ablation than the open surgery group; however, the dynamic risk stratification did not differ between the 2 groups (P = .086).

      Conclusion

      The long-term oncologic outcome of robotic surgery is expected to be comparable with that of open surgery based on the dynamic risk stratification.
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      References

        • Jackson NR
        • Yao L
        • Tufano RP
        • Kandil EH
        Safety of robotic thyroidectomy approaches: Meta-analysis and systematic review.
        Head Neck. 2014; 36: 137-143
        • Kandil E
        • Hammad AY
        • Walvekar RR
        • Hu T
        • Masoodi H
        • Mohamed SE
        • et al.
        Robotic thyroidectomy versus nonrobotic approaches: A meta-analysis examining surgical outcomes.
        Surg Innov. 2016; 23: 317-325
        • Lang BH
        • Wong CK
        • Tsang JS
        • Wong KP
        • Wan KY
        A systematic review and meta-analysis comparing surgically-related complications between robotic-assisted thyroidectomy and conventional open thyroidectomy.
        Ann Surg Oncol. 2014; 21: 850-861
        • Pan JH
        • Zhou H
        • Zhao XX
        • Ding H
        • Wei L
        • Qin L
        • et al.
        Robotic thyroidectomy versus conventional open thyroidectomy for thyroid cancer: A systematic review and meta-analysis.
        Surg Endosc. 2017; 31: 3985-4001
        • Son SK
        • Kim JH
        • Bae JS
        • Lee SH
        Surgical safety and oncologic effectiveness in robotic versus conventional open thyroidectomy in thyroid cancer: A systematic review and meta-analysis.
        Ann Surg Oncol. 2015; 22: 3022-3032
        • Wang YC
        • Liu K
        • Xiong JJ
        • Zhu JQ
        Robotic thyroidectomy versus conventional open thyroidectomy for differentiated thyroid cancer: Meta-analysis.
        J Laryngol Otol. 2015; 129: 558-567
        • Tae K
        • Ji YB
        • Cho SH
        • Lee SH
        • Kim DS
        • Kim TW
        Early surgical outcomes of robotic thyroidectomy by a gasless unilateral axillo-breast or axillary approach for papillary thyroid carcinoma: 2 years' experience.
        Head Neck. 2012; 34: 617-625
        • Tae K
        • Song CM
        • Ji YB
        • Sung ES
        • Jeong JH
        • Kim DS
        Oncologic outcomes of robotic thyroidectomy: 5-year experience with propensity score matching.
        Surg Endosc. 2016; 30: 4785-4792
        • Yi O
        • Yoon JH
        • Lee YM
        • Sung TY
        • Chung KW
        • Kim TY
        • et al.
        Technical and oncologic safety of robotic thyroid surgery.
        Ann Surg Oncol. 2013; 20: 1927-1933
        • Momesso DP
        • Tuttle RM
        Update on differentiated thyroid cancer staging.
        Endocrinol Metab Clin North Am. 2014; 43: 401-421
        • Tarasova VD
        • Tuttle RM
        A risk-adapted approach to follow-up in differentiated thyroid cancer.
        Rambam Maimonides Med J. 2016; 7https://doi.org/10.5041/RMMJ.10231
        • Tuttle RM
        • Tala H
        • Shah J
        • Leboeuf R
        • Ghossein R
        • Gonen M
        • et al.
        Estimating risk of recurrence in differentiated thyroid cancer after total thyroidectomy and radioactive iodine remnant ablation: Using response to therapy variables to modify the initial risk estimates predicted by the new American Thyroid Association staging system.
        Thyroid. 2010; 20: 1341-1349
        • Jeon MJ
        • Kim WG
        • Park WR
        • Han JM
        • Kim TY
        • Song DE
        • et al.
        Modified dynamic risk stratification for predicting recurrence using the response to initial therapy in patients with differentiated thyroid carcinoma.
        Eur J Endocrinol. 2014; 170: 23-30
        • Momesso DP
        • Vaisman F
        • Yang SP
        • Bulzico DA
        • Corbo R
        • Vaisman M
        • et al.
        Dynamic risk stratification in patients with differentiated thyroid cancer treated without radioactive iodine.
        J Clin Endocrinol Metab. 2016; 101: 2692-2700
        • Park S
        • Kim WG
        • Song E
        • Oh HS
        • Kim M
        • Kwon H
        • et al.
        Dynamic risk stratification for predicting recurrence in patients with differentiated thyroid cancer treated without radioactive iodine remnant ablation therapy.
        Thyroid. 2017; 27: 524-530
        • Castagna MG
        • Maino F
        • Cipri C
        • Belardini V
        • Theodoropoulou A
        • Cevenini G
        • et al.
        Delayed risk stratification, to include the response to initial treatment (surgery and radioiodine ablation), has better outcome predictivity in differentiated thyroid cancer patients.
        Eur J Endocrinol. 2011; 165: 441-446
        • Voutilainen PE
        • Siironen P
        • Franssila KO
        • Sivula A
        • Haapiainen RK
        • Haglund CH
        AMES, MACIS and TNM prognostic classifications in papillary thyroid carcinoma.
        Anticancer Res. 2003; 23: 4283-4288
        • Lang BH
        • Lo CY
        • Chan WF
        • Lam KY
        • Wan KY
        Staging systems for papillary thyroid carcinoma: A review and comparison.
        Ann Surg. 2007; 245: 366-378
        • Schlumberger M
        • Catargi B
        • Borget I
        • Deandreis D
        • Zerdoud S
        • Bridji B
        • et al.
        Strategies of radioiodine ablation in patients with low-risk thyroid cancer.
        N Engl J Med. 2012; 366: 1663-1673
        • Giovanella L
        • Ceriani L
        • Suriano S
        • Ghelfo A
        • Maffioli M
        Thyroglobulin measurement before rhTSH-aided 131I ablation in detecting metastases from differentiated thyroid carcinoma.
        Clin Endocrinol. 2008; 69: 659-663
        • Nascimento C
        • Borget I
        • Troalen F
        • Al Ghuzlan A
        • Deandreis D
        • Hartl D
        • et al.
        Ultrasensitive serum thyroglobulin measurement is useful for the follow-up of patients treated with total thyroidectomy without radioactive iodine ablation.
        Eur J Endocrinol. 2013; 169: 689-693
        • Edge SB
        • Compton CC
        The American Joint Committee on Cancer: The 7th edition of the AJCC cancer staging manual and the future of TNM.
        Ann Surg Oncol. 2010; 17: 1471-1474
        • Kim EY
        • Kim TY
        • Kim WG
        • Yim JH
        • Han JM
        • Ryu JS
        • et al.
        Effects of different doses of radioactive iodine for remnant ablation on successful ablation and on long-term recurrences in patients with differentiated thyroid carcinoma.
        Nucl Med Commun. 2011; 32: 954-959
        • Lee SG
        • Lee J
        • Kim MJ
        • Choi JB
        • Kim TH
        • Ban EJ
        • et al.
        Long-term oncologic outcome of robotic versus open total thyroidectomy in PTC: A case-matched retrospective study.
        Surg Endosc. 2016; 30: 3474-3479
        • Durante C
        • Montesano T
        • Attard M
        • Torlontano M
        • Monzani F
        • Costante G
        • et al.
        Long-term surveillance of papillary thyroid cancer patients who do not undergo postoperative radioiodine remnant ablation: Is there a role for serum thyroglobulin measurement?.
        J Clin Endocrinol Metab. 2012; 97: 2748-2753
        • Kim TY
        • Kim WB
        • Kim ES
        • Ryu JS
        • Yeo JS
        • Kim SC
        • et al.
        Serum thyroglobulin levels at the time of 131I remnant ablation just after thyroidectomy are useful for early prediction of clinical recurrence in low-risk patients with differentiated thyroid carcinoma.
        J Clin Endocrinol Metab. 2005; 90: 1440-1445
        • Kim WG
        • Yoon JH
        • Kim WB
        • Kim TY
        • Kim EY
        • Kim JM
        • et al.
        Change of serum antithyroglobulin antibody levels is useful for prediction of clinical recurrence in thyroglobulin-negative patients with differentiated thyroid carcinoma.
        J Clin Endocrinol Metab. 2008; 93: 4683-4689
        • Mallick U
        • Harmer C
        • Yap B
        • Wadsley J
        • Clarke S
        • Moss L
        • et al.
        Ablation with low-dose radioiodine and thyrotropin alfa in thyroid cancer.
        N Engl J Med. 2012; 366: 1674-1685
        • Webb RC
        • Howard RS
        • Stojadinovic A
        • Gaitonde DY
        • Wallace MK
        • Ahmed J
        • et al.
        The utility of serum thyroglobulin measurement at the time of remnant ablation for predicting disease-free status in patients with differentiated thyroid cancer: A meta-analysis involving 3947 patients.
        J Clin Endocrinol Metab. 2012; 97: 2754-2763
        • Pitoia F
        • Bueno F
        • Urciuoli C
        • Abelleira E
        • Cross G
        • Tuttle RM
        Outcomes of patients with differentiated thyroid cancer risk-stratified according to the American thyroid association and Latin American thyroid society risk of recurrence classification systems.
        Thyroid. 2013; 23: 1401-1407