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Letter| Volume 165, ISSUE 3, P664-667, March 2019

Reply to: Insufficient number of examined lymph nodes may offset the survival benefit from neoadjuvant therapy in esophageal squamous cell carcinoma

Published:November 19, 2018DOI:https://doi.org/10.1016/j.surg.2018.10.019
Reply to: Insufficient number of examined lymph nodes may offset the survival benefit from neoadjuvant therapy in esophageal squamous cell carcinoma
Previous ArticleAn insufficient number of examined lymph nodes may offset the survival benefit from neoadjuvant therapy in esophageal squamous cell carcinoma
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      We appreciate the interest and comment of Yang et al referencing our study on timing of esophagectomy after neoadjuvant chemoradiation.
      • Franko J.
      • McAvoy S.
      Timing of esophagectomy after neoadjuvant chemoradiation treatment in squamous cell carcinoma.
      Surgery. 2018; 164: 455-459
      The extent of lymphadenectomy remains a controversial issue in the care of patients with esophageal cancer with good evidence supporting the quest for a greater yield of lymph nodes
      • Visser E.
      • Markar S.R.
      • Ruurda J.P.
      • Hanna G.B.
      • van Hillegersberg R.
      Prognostic value of lymph node yield on overall survival in esophageal cancer patients: a systematic review and meta-analysis.
      Ann Surg. 2018; https://doi.org/10.1097/SLA.0000000000002824
      as well as evidence documenting no association of postresection lymph node count on survival.
      • Lagergren J.
      • Mattsson F.
      • Zylstra J.
      • Chang F.
      • Gossage J.
      • Mason R.
      • et al.
      Extent of lymphadenectomy and prognosis after esophageal cancer surgery.
      JAMA Surg. 2016; 151: 32-39
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      References

        • Franko J.
        • McAvoy S.
        Timing of esophagectomy after neoadjuvant chemoradiation treatment in squamous cell carcinoma.
        Surgery. 2018; 164: 455-459
        View in Article
        • Visser E.
        • Markar S.R.
        • Ruurda J.P.
        • Hanna G.B.
        • van Hillegersberg R.
        Prognostic value of lymph node yield on overall survival in esophageal cancer patients: a systematic review and meta-analysis.
        Ann Surg. 2018; https://doi.org/10.1097/SLA.0000000000002824
        View in Article
        • Lagergren J.
        • Mattsson F.
        • Zylstra J.
        • Chang F.
        • Gossage J.
        • Mason R.
        • et al.
        Extent of lymphadenectomy and prognosis after esophageal cancer surgery.
        JAMA Surg. 2016; 151: 32-39
        View in Article
        • Franko J.
        • Voynov G.
        • Goldman C.D.
        Esophagectomy timing after neoadjuvant therapy for distal esophageal adenocarcinoma.
        The Annals of Thoracic Surgery. 2016; 101: 1123-1130
        View in Article
        • Mariette C.
        • Dahan L.
        • Mornex F.
        • Maillard E.
        • Thomas P.A.
        • Meunier B.
        • et al.
        Surgery alone versus chemoradiotherapy followed by surgery for stage I and II esophageal cancer: final analysis of randomized controlled phase III trial FFCD 9901.
        J Clin Oncol. 2014; 32: 2416-2422
        View in Article

      Article info

      Publication history

      Published online: November 19, 2018
      Accepted: October 12, 2018
      Received: October 6, 2018

      Identification

      DOI: https://doi.org/10.1016/j.surg.2018.10.019

      Copyright

      © 2018 Elsevier Inc. All rights reserved.

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