Invited commentary: Evolving landscape of postoperative hyperamylasemia, postoperative acute pancreatitis, and postoperative pancreatic fistula: Time for a unifying definition

Published:November 27, 2020DOI:
      Pancreatic resection has developed remarkably through the years. Technical finesse and experience have evolved, but the learning curve of a pancreatoduodenectomy is long, and the learning continues throughout the surgeons’ career. Despite all the progress, perioperative complications and mortality rates persist worldwide at approximately 30% and 3%, respectively. Postoperative pancreatic fistula (POPF), post-pancreatectomy hemorrhage (PPH), delayed gastric emptying, biliary leaks, and chyle leaks are universally acknowledged and well-documented complications during the past 2 decades.
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        • Connor S.
        Defining post-operative pancreatitis as a new pancreatic specific complication following pancreatic resection.
        HPB (Oxford). 2016; 18: 642-651
        • Rudis J.
        • Ryska M.
        Pancreatic leakage and acute postoperative pancreatitis after proximal pancreatoduodenectomy.
        Rozhl Chir. 2014; 93: 380-385
        • Bannone E.
        • Andrianello S.
        • Marchegiani G.
        • et al.
        Postoperative acute pancreatitis following pancreaticoduodenectomy: A determinant of fistula potentially driven by the intraoperative fluid management.
        Ann Surg. 2018; 268: 815-822