Multidisciplinary treatment algorithms for rectal cancer are often complex and may
take many months to complete. Total neoadjuvant treatment for locally advanced rectal
cancer, for example, typically includes systemic induction chemotherapy followed by
short-course radiotherapy or long-course chemotherapy, and then surgical resection
several weeks later. With a subsequent postoperative recovery, the patient may spend
the better part of a year in treatment. If a temporary diverting stoma is required,
there may be a further delay to restoration of bowel continuity.
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References
- Low anterior resection syndrome score: development and validation of a symptom-based scoring system for bowel dysfunction after low anterior resection for rectal cancer.Ann Surg. 2012; 255: 922-928
- Assessment of long-term bowel dysfunction after restorative proctectomy for neoplastic disease: a population-based cohort study.Surg Oncol. 2022; 172: 782-788
- International consensus definition of low anterior resection syndrome.Colorectal Dis. 2020; 22: 331-341
- Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic cancers.Cochrane Database Syst Rev. 2018; 1CD012529
Article info
Publication history
Published online: May 31, 2022
Accepted:
April 29,
2022
Identification
Copyright
© 2022 Published by Elsevier Inc.
