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Big data exposes the tip of the LARS iceberg

      Multidisciplinary treatment algorithms for rectal cancer are often complex and may take many months to complete. Total neoadjuvant treatment for locally advanced rectal cancer, for example, typically includes systemic induction chemotherapy followed by short-course radiotherapy or long-course chemotherapy, and then surgical resection several weeks later. With a subsequent postoperative recovery, the patient may spend the better part of a year in treatment. If a temporary diverting stoma is required, there may be a further delay to restoration of bowel continuity.
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