Dr. Barbra Miller (Columbus, OH): Many of the factors that you've listed involve interpretation and
are subjective, such as shape, margins, heterogeneity, fat infiltration. This is similar
to the American Thyroid Association criteria and Thyroid Imaging Reporting and Data
Systems when looking at thyroid nodules. Have you looked at any measures that can
be characterized in an objective fashion? There are the terms such as sphericity undulation,
eccentricity, entropy, and/or compactness?
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Published online: October 13, 2022
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© 2022 Elsevier Inc. Published by Elsevier Inc. All rights reserved.