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Invited commentary on: “Euglycemic diabetic ketoacidosis after pancreaticoduodenectomy”

Published:November 26, 2022DOI:https://doi.org/10.1016/j.surg.2022.10.021
      Euglycemic diabetic ketoacidosis (EDKA), which was first described by Munro et al
      • Munro J.F.
      • Campbell I.W.
      • McCuish A.C.
      • Duncan L.J.P.
      Euglycaemic diabetic ketoacidosis.
      in 1973, is a clinical syndrome characterized by euglycemia (blood glucose <250 mg/dL) in the presence of severe metabolic acidosis (arterial pH <7.3; serum bicarbonate <18 mEq/L) and ketonemia. In EDKA, delayed diagnosis and treatment (due to the absence of hyperglycemia) might induce serious and severe and life-threatening complications. In particular, EDKA after pancreaticoduodenectomy (PD) is still poorly understood and under-recognized, primarily because no large studies have specifically evaluated EDKA after PD; current literature is limited to case reports.
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      References

        • Munro J.F.
        • Campbell I.W.
        • McCuish A.C.
        • Duncan L.J.P.
        Euglycaemic diabetic ketoacidosis.
        Br Med J. 1973; 2: 578-580
        • Sinha N.
        • Venkatram S.
        • Diaz-Fuentes G.
        Starvation ketoacidosis: a cause of severe anion gap metabolic acidosis in pregnancy.
        Case Rep Crit Care. 2014; 2014: 906283
        • Modi A.
        • Agrawal A.
        • Morgan F.
        Euglycemic diabetic ketoacidosis: a review.
        Curr Diabetes Rev. 2017; 13: 315-321
        • Yu X.
        • Zhang S.
        • Zhang L.
        Newer perspectives of mechanisms for euglycemic diabetic ketoacidosis.
        Int J Endocrinol. 2018; 2018: 7074868

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