Invited commentary on: “Euglycemic diabetic ketoacidosis after pancreaticoduodenectomy”

Published:November 26, 2022DOI:
      Euglycemic diabetic ketoacidosis (EDKA), which was first described by Munro et al
      • Munro J.F.
      • Campbell I.W.
      • McCuish A.C.
      • Duncan L.J.P.
      Euglycaemic diabetic ketoacidosis.
      in 1973, is a clinical syndrome characterized by euglycemia (blood glucose <250 mg/dL) in the presence of severe metabolic acidosis (arterial pH <7.3; serum bicarbonate <18 mEq/L) and ketonemia. In EDKA, delayed diagnosis and treatment (due to the absence of hyperglycemia) might induce serious and severe and life-threatening complications. In particular, EDKA after pancreaticoduodenectomy (PD) is still poorly understood and under-recognized, primarily because no large studies have specifically evaluated EDKA after PD; current literature is limited to case reports.
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