We have read the article “Hypercalcemia with a Parathyroid Hormone Level of ≤50 pg/mL:
Is This Primary Hyperparathyroidism?” by Wang R et al, with full interest.
1
At the outset, we appreciate the contribution and efforts of authors in highlighting
the dilemma of biochemical confirmation of primary hyperparathyroidism (PHPT) in the
absence of raised parathyroid hormone (PTH). We have some queries and comments.To read this article in full you will need to make a payment
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References
- Hypercalcemia with a parathyroid hormone level of ≤50 pg/mL: is this primary hyperparathyroidism?.Surgery. 2023; 173: 154-159
- Should the duration of primary hyperparathyroidism impact guidelines for evaluation and treatment?.Surgery. 2019; 165: 105-106
- Disagreement: should the duration of primary hyperparathyroidism impact guidelines for evaluation and treatment?.Surgery. 2019; 166: 949-950
Article info
Publication history
Published online: January 07, 2023
Accepted:
November 14,
2022
Publication stage
In Press Corrected ProofIdentification
Copyright
© 2023 Elsevier Inc. All rights reserved.
ScienceDirect
Access this article on ScienceDirectLinked Article
- Hypercalcemia with a parathyroid hormone level of ≤50 pg/mL: Is this primary hyperparathyroidism?SurgeryVol. 173Issue 1
- PreviewPrimary hyperparathyroidism is characterized by hypercalcemia with inappropriately normal or elevated parathyroid hormone. However, the absolute parathyroid hormone value that is defined as inappropriately normal is unclear. We reviewed our experience with parathyroidectomy in patients with hypercalcemia and parathyroid hormone of ≤50.0 pg/mL (normal range 12.0–88.0 pg/mL).
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- Response to: Hypercalcemia with a parathyroid hormone level of ≤50 pg/mL: Is this primary hyperparathyroidism?Surgery
- PreviewWe appreciate the attention Sharma et al has paid to our article, "Hypercalcemia with a parathyroid hormone level of ≤50 pg/mL: Is this primary hyperparathyroidism?"1 Sharma et al. raised a question regarding the appropriateness of bilateral parathyroid exploration in primary hyperparathyroidism. We found that patients with hypercalcemia and parathyroid hormone (PTH) levels ≤50 pg/mL had pathology-proven hypercellular parathyroid glands and similar clinical presentation and surgical outcomes to those with PTH >50 pg/mL.
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