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Original communication| Volume 3, ISSUE 5, P670-678, May 1938

Primary carcinoma of the biliary system

A clinicopathological analysis of forty cases
  • Rigney D'Aunoy
    Affiliations
    From the Departments of Pathology and Bacteriology, Charity Hospital of Louisiana at New Orleans, New Orleans, La., USA

    From the School of Medicine, Louisiana State University Medical Center New Orleans, La., USA
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  • Michael Alexander Ogden
    Affiliations
    From the Departments of Pathology and Bacteriology, Charity Hospital of Louisiana at New Orleans, New Orleans, La., USA

    From the School of Medicine, Louisiana State University Medical Center New Orleans, La., USA
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  • Béla Halpert
    Affiliations
    From the Departments of Pathology and Bacteriology, Charity Hospital of Louisiana at New Orleans, New Orleans, La., USA

    From the School of Medicine, Louisiana State University Medical Center New Orleans, La., USA
    Search for articles by this author
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      Abstract

      In 6,050 necropsies performed on persons over one year of age, there were 40 primary carcinomas of the biliary system. Of these, 23 were primary in the liver (16 liver cell and 7 cylindrical cell carcinomas); 6 were primary in the extrahepatic biliary ducts (all cylindrical cell carcinomas); 11 occurred primarily in the gallbladder (all cylindrical cell carcinomas).
      Eight of the patients died in the fifth, 11 in the sixth, and 14 in the seventh decade of life. The youngest patient was thirteen years of age and the oldest was seventy-seven years of age.
      In many instances, in addition to local infiltration or spread by lymph and blood channels, metastases occurred in regional lymph nodes or distant organs.
      Practically all of the patients with primary liver growths had cirrhosis of the liver with ascites.
      Most of the patients with primary growths in the extrahepatic biliary ducts and the gallbladder had cholelithiasis.
      With few exceptions all of the patients were jaundiced.
      The average duration of illness was four and one-half months.
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