Original communication| Volume 4, ISSUE 4, P552-561, October 1938

Treatment of the undescended testis: With special reference to therapy with hormones

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      Treatment of the retained gonad may be deferred until the patient is 9 to 11 years old. With the hope that the ease may be a favorable one, a course of treatment with pituitary-like substance may be tried first in cryptorchids before surgical procedures. Reports in the literature of cryptorchids treated by gonadotropic hormones reveal that in as high as 70 per cent of the cases there is descent of the testis into the scrotum. This form of therapy has been less efficacious in the cases treated to date at this clinic, degrees of descent being obtained in only 16 per cent of the cases so treated. No untoward effects resulting from hormonal therapy have been observed.
      For reasons mentioned elsewhere, it is believed that endocrine imbalance alone does not fully explain the cause or give a rational basis for treatment in all cases of true testicular maldescent. However, gonadotropic substance should be given at least a preliminary trial in the treatment of undescended testis, and, if no results are obtained, an orchiopexy should be performed.
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