This paper is only available as a PDF. To read, Please Download here.
Treatment of the retained gonad may be deferred until the patient is 9 to 11 years old. With the hope that the ease may be a favorable one, a course of treatment with pituitary-like substance may be tried first in cryptorchids before surgical procedures. Reports in the literature of cryptorchids treated by gonadotropic hormones reveal that in as high as 70 per cent of the cases there is descent of the testis into the scrotum. This form of therapy has been less efficacious in the cases treated to date at this clinic, degrees of descent being obtained in only 16 per cent of the cases so treated. No untoward effects resulting from hormonal therapy have been observed.
For reasons mentioned elsewhere, it is believed that endocrine imbalance alone does not fully explain the cause or give a rational basis for treatment in all cases of true testicular maldescent. However, gonadotropic substance should be given at least a preliminary trial in the treatment of undescended testis, and, if no results are obtained, an orchiopexy should be performed.
To read this article in full you will need to make a payment
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to Surgery
Already a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
- The Undescended Testis.Arch. Surg. 1927; 14 (Quoted by Wangensteen, O. H.): 663
Monod, C., and Terrillon, O.: Quoted by Wangensteen.
- Ueber Kryptorchismus und seine Behandlung.Beitr. z. klin. Chir. 1898; 21: 445
- War Department Report: Defects Found in Drafted Men.Statistical Information Compiled from the Draft Records. 1920; (Washington, D. C.): 164
- Abstract of the Hunterian Lectures on the Anatomy, Physiology, and Pathology of the Imperfectly Descended Testes.Brit. M. J. 1902; 1: 503
- The Surgical Treatment of Undescended Testicle: A Further Contribution.J. A. M. A. 1903; 41: 718
- Operative Treatment of Undescended or Maldescended Testes with Special Reference to End Results.Surg., Gynec. & Obst. 1919; 28: 452
- The Undescended Testis—An Experimental and Clinical Study.Arch. Surg. 1927; 14: 663
- The Surgery of the Undescended Testis.Surg., Gynec. & Obst. 1932; 54: 219
- The Undescended Testis: Its Fate After Satisfactory Scrotal Anchorage.Ann. Surg. 1935; 102: 875
Berger, P.: Quoted by Meyer.
Hofstätter, R.: Quoted by Meyer and Wangensteen.
- Die Pathologie der Hodenretention.Arch. f. klin. Chir. 1913; 100: 1151
- Die Pathologie der Hodenretention.Arch. f. klin. Chir. 1913; 101: 150
- Clinical Study of the Spermatogenesis of Undescended Testicles.Arch. Surg. 1935; 31: 290
- Klinische Studien über die Wirkung des Hypophysenvorderlappens auf der Mannlichen Genital-apparat.Ztschr. f. Klin. Med. 1930; 114: 610
- The Treatment of Undescended Testis with Anterior Pituitary-like Substance.Endocrinology. 1937; 21: 220
- Evaluation of Hormone Therapy for Undescended Testis in Man.Endocrinology. 1937; 21: 230
- The Effects of Extracts of Pregnancy Urine upon Hypopituitarism in the Male.J. Pediat. 1934; 4: 775
- Urinary Excretion of Gonadotropic Hormone in Cryptorchidism.J. A. M. A. 1937; 108: 352
- Clinical Manifestations of Dysfunction of Anterior Pituitary.J. A. M. A. 1935; 104: 464
- Effect of Extracts of the Anterior Pituitary and Similar Active Principles of Blood and Urine, Chap. XVI. Sex and Internal Secretion.Williams and Wilkins, Baltimore1934
- The Effect on the Reproductive System of Ablation and Implantation of the Anterior Hypophysis, Chap. XV. Sex and Internal Secretion.Williams and Wilkins, Baltimore1934
- The Quantitative Determination of Small Amounts of Gonadotropic Material.J. Biol. Chem. 1934; 106: 125
- Treatment of Cryptorchidism with Gonadotropic Hormones.in: Proc. Inst. Med. Chicago. 11. 1937: 324
- The Treatment of Imperfect Descent of the Testis with Gonadotropic Hormones.Lancet. 1937; 232: 497
- Treatment of Undescended Testes by Injection of Prolan.New York State J. Med. 1933; 33: 1095
- Further Consideration of the Properties of the Gonad-stimulating Principle of Mare Serum.Am. J. Physiol. 1932; 102: 227
- III. Treatment of Several Types of Adipogenital Dystrophy in Boys with Particular Reference to the Use of Gonadotropic Hormone from the Urine of Pregnant Women for Their Imperfectly Developed Genitals.J. Pediat. 1936; 8: 704
- Undescended Testes in Man and Rhesus Monkeys.J. A. M. A. 1935; 130: 314
- Prostatic Hypertrophy.Am. J. Roentgenol. 1937; 38: 389
- The Difference of Response of Males with Undescended Testes to the Water Soluble (Anterior Pituitary-like) Fraction of Pregnancy Urine.Endocrinology. 1936; 20: 192
- Biology of the Testis, Chap. VII. Sex and Internal Secretion.Williams and Wilkins, Baltimore1934
- The Relationship of Cryptorchidism to Tumors of the Testes.J. Urol. 1936; 35: 378
- Ueber die histologischen Veränderungen des Hodens, Nebenhodens und Samenleiters von Gerburt an bis Greisenalter.Anat. Hefte Herausgegeben von Merkel u. Bonnet. 1901; 18: 599
- A Summary of the Anatomy of the Infant and Child.Abt's Pediatrics. 1923; 1: 358
Crampton, C. W.: Quoted by Wangensteen.
Received: May 10, 1938
☆Supported by a grant from the research funds of the Graduate School.
© 1938 Published by Elsevier Inc.