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Original communication| Volume 4, ISSUE 5, P680-686, November 1938

The use of vitamin B1 in the preoperative preparation of the hyperthyroid patient

  • William D. Frazier
    Affiliations
    From the Surgical Service of the Hospital of the University of Pennsylvania Philadelphia, Pa. USA

    From the Harrison Department of Surgical Research, School of Medicine, University of Pennsylvania Philadelphia, Pa. USA
    Search for articles by this author
  • I.S. Ravdin
    Affiliations
    From the Surgical Service of the Hospital of the University of Pennsylvania Philadelphia, Pa. USA

    From the Harrison Department of Surgical Research, School of Medicine, University of Pennsylvania Philadelphia, Pa. USA
    Search for articles by this author
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      Abstract

      It is our opinion that the severely thyrotoxic patients have been benefited by the administration of vitamin B1. Not only is the nutritional state improved, as evidenced by increased appetite and weight gain, but also patients with severe hyperthyroidism can be adequately prepared for operation in a shorter time. That the vitamin treated cases showed a greater fall in heart rate during the preparatory period suggests that the tachycardia may have been due, in part, to a vitamin B deficiency and, therefore, was improved by the administration of adequate amounts of this vitamin.
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