Bacterial agglutinin in bile of patients with cholelithiasis

Julian A. Sterling, M.D.
Julian A. Sterling
Affiliations
From the Harrison Department of Surgical Research, Schools of Medicine, University of Pennsylvania, and the Hospital of the University of Pennsylvania, Philadelphia, PA, USA
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Abstract

1.
1. Agglutinin titer for the staphylococcus, B. colt, and B. typhosus was determined in the serum, gall-bladder bile, and hepatic bile obtained at operation from a series of 23 patients.
2.
2. In the specimens obtained from the patients who did not have gallstones, no agglutinin was present in hepatic bile; and agglutinin was present only to the colon bacillus in the gall-bladder bile of 1 of 6 patients. The serum of these patients contained bacterial agglutinin in low titer.
3.
3. The hepatic bile in the patients with cholelithiasis contained agglutinin in 2 of 6 instances. The gall-bladder bile contained agglutinin in every one of the 1.2 patients with calculi. The serum agglutinin titer in these patients with gallstones was high.
4.
4. The presence of bacterial agglutinin in patients who have cholelithiasis and the absence of bacterial agglutinin in those patients who do not have biliary calculi may be of significance in the etiology of gallstones

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- Riegel Cecilia
- Ravdin I.S.
- Johnston C.G.
Studies of Gall-Bladder Function. VI. The Absorption of Bile Salts and Cholesterol From the BileFree Gall Bladder.
Am. J. Physiol. 1932; 99: 656
- Crossref
- Google Scholar
- Sterling J.A.
Agglutinins in the Bile of Dogs.
in: Proc. Soc. Exper. Biol. & Med.33. 1935: 251
- Google Scholar
- Sterling J.A.
Agglutinins in the Serum and Bite of Dogs Following Cholecystitis Produced by Infections of Typhoid Bacilli.
Surgery. 1939; 5: 663
- Google Scholar

Received: December 20, 1938

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