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Abstract
In an attempt to simulate the conditions which exist after an acute abdominal catastrophe
such as the rupture of a peptic ulcer, the rupture of an acutely inflamed appendix,
or the rupture of a section of gangrenous bowel, the above series of experiments were
performed. In addition to the severe systemic reaction produced on the animals by
these procedures, there was a notable tendency for the leucocyte count in the peripheral
blood to fall. It seems reasonable to assume that such a drop in the leucocyte count
may occur under similar circumstances in man, and that it has not been previously
detected except in isolated cases is probably due to the fact that blood studies were
not made at the appropriate times. If such a fall in the leucocytes does occur in
man it may explain some of the unexpectedly low leucocyte counts which are not infrequently
found.
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Article info
Publication history
Received:
March 31,
1942
Identification
Copyright
© 1943 Published by Elsevier Inc.
