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Original communication| Volume 13, ISSUE 2, P214-223, February 1943

The effect of atropine on gastric secretion during the night

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      Abstract

      • 1.
        1. The nightly gastric secretion of fifty normal and fifteen ulcer patients was studied on each of two successive nights, the first night serving as a control, with atropine being given by proctoclysis the second night.
      • 2.
        2. In the control period, mean values indicate that the secretory rate, volume of secretion, free and total acidity are higher for the ulcer group. Atropine diminished the volume of secretion as well as the free and total acidity in both the normal and ulcer series. The decrease in these values was more pronounced in the ulcer group.
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