This paper is only available as a PDF. To read, Please Download here.
B. histolyticus was demonstrated in cultures taken from débrided tissues in 17 civil wounds. There were 7 compound fractures, 5 lacerations, 3 gunshot wounds, and 2 burns. These are believed to be the first records of B. histolyticus in connection with burns.
Only 1 case, that of a compound fracture, proved fatal. This was a typical case of gaseous gangrene caused by B. perfringens and other bacteria. The typical lesions produced by pure infections of B. histolyticus were probably masked and were not recognized.
All of the other patients recovered and the peculiar lesions of infection by B. histolyticus were not recognized in any case.
Persistence of B. histolyticus in an infected wound was noted in one case of compound fracture of the leg as late as the twenty-fifth day, when the leg had to be amputated. Persistence to the thirty-seventh day was observed also in a case of multiple pistol shot wounds.
The occurrence of B. histolyticus in wounds is regarded solely as an expression of its widespread occurrence in nature. If wounds are promptly and adequately débrided it rarely persists. If gaseous gangrene develops, the peculiar lesions produced by this organism in pure infections are likely to be masked and overlooked. It may persist in a mixed infection for twenty-five to thirty-seven days without giving any clinical indication of its presence.
The comparatively infrequent demonstration of this organism in accidental wounds probably gives an erroneous conception of the actual frequency of its occurrence owing to the fact that it is so easily overlooked in a bacteriologic examination of a mixed infection.
To read this article in full you will need to make a payment
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to Surgery
Already a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
- Anaerobic Infections of War Wounds in the Middle East.Lancet. 1943; 2: 63
- Anaerobic Infections of War Wounds in the Middle East.Lancet. 1943; 2: 94
- Anaerobic Infections of War Wounds in the Middle East.Lancet. 1943; 2: 123
- The Study of the Prevention of Infection in Contaminated Accidental Wounds, Compound Fractures and Burns.Ann. Surg. 1943; 118: 171
- A War-time Study of Civilian Wounds.May 19, 1944 (Address before New York State Association Public Health Laboratories)
- Contribution a l'etiologie de la gàngrene gazeuse.Compt. rend. Acad. d. sc. 1916; 163: 449
- Demonstration des lesions provoques chez le cobaye parle B. histolyticus.Compt. rend. Soc. de biol. 1917; 80: 157
- Gangrène gazeuse de la région scapulaire, avec destruction musculaire causee par le B. histolyticus (Weinberg and Sequin).Compt. rend. Soc. de biol. 1918; 81: 96
- Lesions histolytique produite chez le cobaye par le B. histolytique.Ann. Inst. Pasteur. 1925; 39: 855
- Recovery of Bacillus Histolyticus From Human Feces.in: Proc. Soc. Exper. Biol. & Med. 21. 1923: 198
- Anaerobic Spore-Bearing Bacteria of the Human Intestines in Health and in Certain Diseases.J. Infect. Dis. 1924; 35: 423
- The Isolation of B. Histolyticus From the Ileo-cecal Region of Two Human Intestines.in: Proc. Soc. Exper. Biol. & Med. 22. 1924: 137
- Habitat of B. Histolyticus in Human Intestines.J. Infect. Dis. 1925; 36: 517
- Présence des Anaérobes de la Gàngrene Gazeuse dans lar Flore microbienne de l'appendicite.Compt. rend. Soc. de biol. 1926; 94: 813
- The Isolation of Bacillus Histolyticus From Soil in California.in: Proc. Soc. Exper. Biol. & Med. 20. 1920: 502
- Der Bacillus Histolyticus (Weinberg and Sequin).Zentralbl. f. Bakt. 1925; 94: 81
- A Pharmaco-bacteriologic Study of African Poisoned Arrows.J. Infect. Dis. 1926; 41: 51
- The Aerobic Cultivation of Bacillus Histolyticus.in: Proc. Soc. Exper. Biol. & Med. 20. 1923: 501
Received: March 26, 1945
☆Work done under a contract recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and Columbia University.
© 1945 Published by Elsevier Inc.