This paper is only available as a PDF. To read, Please Download here.
Abstract
- 1.1. The heparin-caronamide enhancement of the therapeutic effectiveness of heparin/gelatin menstruum has been demonstrated in fifteen case studies.
- 2.2. The practical application of this reaction may be expected to reduce the cost of heparin therapy approximately 50 per cent.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to SurgeryAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Enhancement of Penicillin Blood Levels in Man by Means of a New Compound, Caronamide.Am. J. Med. 1947; 3: 206-210
- Caronamide for Increasing Penicillin Plasma Concentration in Man.J.A.M.A. 1947; 134: 1528
- Caronamide for Increasing Penicillin Plasma Concentration in Man.J.A.M.A. 1947; 134: 1532
- Enhancement of Plasma Penicillin Concentration by Caronamide and Sodium Benzoate.J. Lab. & Clin. Med. 1947; 32: 818
- Enhancement of Blood Levels by Caronamide During the Intramuscular Administration of Penicillin.J. Lab. & Clin. Med. 1947; 32: 807
- The Effect of Caronamide Upon Penicillin Therapy of Experimental Pneumococcus and Typhoid Infections in Mice.in: Proc. Soc. Exper. Biol. & Med. 65. 1947: 222-227
- Certain Pharmacologic Properties of 4′-Carboxyphenylmethanesulfonanilide (Caronamide), Including Its Effect on the Renal Clearance of Compounds Other Than Penicillin.J. Pharmacal Exper. Therap. 1947; 91: 272
- New Concepts of the Competitive Inhibition of the Renal Tubular Excretion of Penicillin.Science. 1947; 103: 94
- The Inhibitory Effect of Caronamide on the Renal Elimination of Penicillin.Am. J. Physiol. 1947; 149: 355
- The Inhibitory Effect of Caronamide on the Renal Elimination of Penicillin.Am. J. Physiol. 1947; 149: 368
- The Renal Excretion 4′-Carboxyphenylmethanesulfonanilide (Caronamide) in Biological Fluids.J. Pharmacal & Exper. Therap. 1947; 91: 250
- Note on the Effect of Repeated Intravascular Injections of Heparin.Bull. Johns Hopkins Hosp. 1930; 46: 365
- Skandinav. Arch. f. Physiol. 81. 1938
- Heparin in the Treatment of Thrombosis.(cited by)ed. 2. Oxford Medical Publications, New York1946 (Oxford University Press)
- Acta. med. Skandinav. 1938; 94: 258
- Heparin in the Treatment of Thrombosis.(cited by)ed. 2. Oxford Medical Publications, New York1946 (Oxford University Press)
- The Rate of Excretion of Heparin in Urine Following its Intravenous Injection in Anesthetized Dogs.Am. J. Physiol. 1941; 133: 362
Sirak, Howard, D., McCleery, Robert S., and Artz, Curtis P.: The Effect of Caronamide With Heparin on the Coagulation of Human Blood. A Preliminary Report, Surgery. (To be published.)
- Anticoagulation Therapy With Heparin/Pitkin's Menstruum in Thromboembolic Disease.Am. J. Med. 1947; 3: 447-467
Article info
Footnotes
☆This study was supported in part by a grant from the Comly and Coleman Fund. Heparin/Gelatin Menstruum was supplied by the Upjohn Company, Kalamazoo, Mich., and Caronamide by Sharp & Dohme, Inc., Glenolden, Pa.
☆Read at the meeting of the Society of University Surgeons, New Orleans, La., Jan. 29–31, 1948.
Identification
Copyright
© 1948 Published by Elsevier Inc.
