We have read with great interest the article by Söreide et al (Surgery 1997;122:1117-23)
regarding long-term survival of patients operated on for primary hyperparathyroidism
(HPT), which is a highly valuable contribution to the knowledge on this subject. They
found a high parathyroid hormone excretion to be of independent significance for survival,
although the overall survival of these patients treated at the Mayo Clinic was not
decreased compared with survival of the control group. The latter observation, being
“in contrast to previous Scandinavian studies,” was suggested to be explained by the
fact that their patients series was more current and had milder disease at surgery,
which would bring a favorable survival. Unfortunately, that may not be the only explanation,
because another study on the death risk of 4461 patients operated on for primary HPT
during a more recent period, 1987 to 1994, showed an increased risk of death compared
with the general population, the risk ratio being 1.53 (95% confidence interval 1.40
to 1.67).
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References
- Clinical evaluation of total serum calcium in primary hyperparathyroidism and the risk of death after surgery.Eur J Clin Invest. 1995; 25: 48-52
- Parathyroid adenoma weight and the risk of death after treatment for primary hyperparathyroidism.Surgery. 1995; 117: 134-139
- Increased risk of death from primary hyperparathyroidism—an update.Eur J Clin Invest. 1998; 28: 271-276
- Socioeconomic factors, health behaviours, and mortality.JAMA. 1998; 21: 1703-1708
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© 1999 Mosby, Inc. Published by Elsevier Inc. All rights reserved.